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br Conflict of interest br Acknowledgments We thank Jianru Z
2019-07-15

Conflict of interest Acknowledgments We thank Jianru Zuo (Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China) for providing fbr11-1 seeds. We are grateful to Carol MacKintosh and the DSTT at the University of Dundee (UK) for anti-RD21 antibodies. This
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br Experimental section br Results br Discussion In
2019-07-15

Experimental section Results Discussion In our previous work (Rashidi et al., 2018) we isolated a novel glucarpidase whose raised CEP-32496 is did not cross-react with the one in clinical use. In principle, therefore, it would be possible to delay the production of antibodies in a patient
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Accumulated evidence indicates that apelin
2019-07-15

Accumulated evidence indicates that apelin plays a protective role in ischemic stroke, contributing to post-stroke recovery (Yang et al., 2014; Chen et al., 2015; Xin et al., 2015; Yan et al., 2015). Apelin gene (APLN) encodes prepro-apelin with 77 amino acids, while the C-terminal 23 Ellagic acid a
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In summary we show that PE significantly ameliorate
2019-07-15

In summary, we show that PE significantly ameliorate HCD-induced atherosclerosis in apoE−/− mice. Dietary fiber may influence the intestinal microbiota and thus the circulating levels of SCFAs. SCFAs, such as butyrate, inhibit cholesterol uptake and promote cholesterol excretion from enterocytes. Ou
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Several studies have already shown that mPR activation can s
2019-07-15

Several studies have already shown that mPR activation can significantly reduce intracellular cAMP levels in different kind of cells, such as GT1-7 neuronal cells [32], MDA-MB-468 breast cancer cells [55] and primary vascular endothelial cells [56]. The experiments performed with PTXa and 8-Br-cAMP
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br Declaration of conflicting interests
2019-07-13

Declaration of conflicting interests Funding The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by CT Stem Cell grant # 15-RMB-YALE-07 (to L.E.N), and by an unrestricted Research Gift from
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The key difference between the
2019-07-13

The key difference between the membrane zymography and classical measurements of enzyme activities in soil slurries is the enzyme-substrate accessibility. Classical enzyme assays maximize access of substrate to all potentially reactive enzyme sites by ensuring sample destruction and detachment follo
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UNC 0631 It is of interest that an initial maternal experien
2019-07-13

It is of interest that an initial maternal experience in virgin mice produces both changes in subsequent maternal behavior as well as possible changes in neural gene expression. Stolzenberg et al. (2012) proposed that experience-based changes in maternal responsiveness may be mediated by chromatin m
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br Signaling of DDR receptor and its
2019-07-13

Signaling of DDR2 receptor and its regulation Being the tyrosine kinase receptor, downstream signaling of DDR2 receptor is initiated by phosphorylation of cytoplasmic tyrosine residue upon ligand binding (Type II collagen) but the authentic facts or detail information of tyrosine phosphorylation
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br Results and Discussion br
2019-07-13

Results and Discussion Conclusions Based on their common NTP pyrophosphatase activity, similar size of the catalytic domains, and the conservation of glutamate residues, it was assumed previously that the MazG and HisE families were related to MutT and other Nudix family hydrolases (see Zhang
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Following mutagenesis of the glucarpidase gene of Pseudomona
2019-07-13

Following mutagenesis of the glucarpidase gene of Pseudomonas sp. strain RS-16 [30], approximately 73% of the clones retained enzyme activity, as indicated by the clear zones and yellow precipitate surrounding their colonies. However, there were very few that had ‘halos’ around colonies that were da
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VHb expression in recombinant E coli
2019-07-13

VHb expression in recombinant E. coli expressing P4H improved Hyp production, presumably by enhancing oxygen transfer. VHb expression contributed to improving growth and extending the period of exponential growth in both shaker flask culture and bioreactor fermentation. A similar phenomenon was also
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One possibility to differentiate between the two failure mod
2019-07-13

One possibility to differentiate between the two failure modes, and also to identify the corresponding characteristics of the resulting fracture surface, is a series of FNCT measurements with varying nominal (initial) stress. The dependence of the observed time to failure tf on the actual stress cha
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Although further experiments are needed to determine definit
2019-07-13

Although further experiments are needed to determine definitively whether D–ETB receptor heterodimers exist, for example, by using fluorescence resonance G-1 transfer analysis or co-immunoprecipitation of receptors, the results of the study by Zeng and colleagues appear to indicate that D–ETB recept
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br Transparency document br Introduction Cigarette
2019-07-13

Transparency document Introduction Cigarette smoke is modifiable factors to alter the neurovascular functions. Now a day, cigarette smoking in public place is offense due to toxic exposure cause the neurological and respiratory system damage to non-smoker population [1]. A literature survey ex
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