• The PAX gene encodes a transcriptional factor

  2019-05-21

  

  The PAX5 gene encodes a transcriptional factor, which is specifically expressed at the early stages of B-cell differentiation and it is required for B-cell development. Its dysregulation is involved in the leukemogenesis of B-ALL. The PAX5 gene rearrangements account for approximately 2.5% of pediat

• A structured inherited arrhythmia or heart disease clinic pr

  2019-05-21

  

  A structured inherited arrhythmia (or heart disease) clinic provides the platform for optimized multidisciplinary evaluation and management of patients and families with suspected inherited heart disease. The collective efforts of the core staff and access to a variety of experts in related discipli

• br Mega cohort studies Remote monitoring

  2019-05-21

  

  Mega-cohort studies Remote monitoring collects a wealth of data from large numbers of patients which are not subject to saturation or overwritten memory counters within any implantable device. These databases provide an opportunity to better understand system function, patient condition, and dise

• br Introduction Once metastatic breast cancer cells are in

  2019-05-21

  

  Introduction Once metastatic breast cancer myd88 inhibitor are in the bone marrow, they hijack signals coming from the normal bone remodelling process and promote bone degradation [1]. Bone degradation is caused by osteoclasts, which have the unique property to dissolve bone mineral and degrade

• For single shot techniques like the CBA a modified

  2019-05-21

  

  For single-shot techniques, like the CBA, a modified spiral mapping catheter has been introduced for the identification of PVPs prior to ablation and also for monitoring purposes during the ablation process [6]. The Achieve™ Mapping Catheter (AC) is an intra-cardiac electrophysiological diagnostic c

• cftr De hecho la Am rica po tica

  2019-05-21

  

  De hecho la América poética comparte con estos periódicos especializados un mismo receptor, una misma nómina de suscriptores que gustan de la poesía lírica, un mismo “público ilustrado e igualmente sensible cftr la razón del filósofo y al arte del poeta romántico” (Batticuore: 113). Estas revistas t

• El trasfondo musical de la obra de sor Juana

  2019-05-21

  

  El trasfondo musical de la obra de sor Juana Inés de la Cruz ha recibido la atención de connotados críticos, tanto del ámbito de la música como del de las letras. Quien parece haber inaugurado en toda forma esta veta crítica es Alfonso Méndez Plancarte en su admirable anotación de la obra de sor Jua

• Autophagy can be generally divided into

  2019-05-21

  

  Autophagy can be generally divided into non-selective bulk autophagy and selective autophagy. Non-selective autophagy breaks down proteins and organelles to provide the cell with nutrients in response to starvation. Selective autophagy removes damaged and excess organelles as well as protein RG2833

• Babies and children feature heavily in this August issue of

  2019-05-21

  

  Babies and children feature heavily in this August issue of , as well they should at a time when unfinished agendas are top of the agenda. In its 2014 report on the , released on July 7, the UN described the under-5 mortality goal as “slipping away from achievement by 2015”. The research and opinio

• br Stephanie Topp points to the limitations

  2019-05-21

  

  Stephanie Topp points to the limitations of quality measurement in Commission on High Quality Health Systems (HQSS Commission; May, 2017) that might not fit the real-world contexts of low-income and middle-income countries (LMICs). She also takes issue with a narrow set of generic indicators and

• br What is the best pacing

  2019-05-20

  

  What is the best pacing algorithm for vasovagal syncope? Conclusions Conflict of interest Introduction The number of implantations of cardiovascular implantable electronic devices (CIEDs), including permanent pacemakers (PPMs), implantable cardioverter defibrillators (ICDs), and cardiac

• Entre las publicaciones de indagaci n epistemol gica se

  2019-05-20

  

  Entre las publicaciones de indagación epistemológica se incluyen aquellas que plantean los cuestionamientos al pensamiento científico de la época y otras que reflexionan sobre la investigación científica, sus desarrollos y consecuencias iatrogénicas. Sobre estos particulares, se destaca la necesidad

• Although high and variable frequencies of sickle cell trait

  2019-05-20

  

  Although high and variable frequencies of sickle cell trait in different ethnic groups in Uganda have been reported previously, those data were from around 70 years ago and were based on small sample sizes. Thus, the findings of Ndeezi and colleagues provide a contemporary overview that is nationall

• De acuerdo con Oliver los

  2019-05-20

  

  De acuerdo con Oliver, los estados latinoamericanos reformados son las formas políticas que han abierto las puertas para que el poder financiero global domine las economías nacionales, imponga una globalización unilateral y haya difundido por todos los medios la ideología y las políticas neoliberale

• De acordo com algumas pesquisas os neo pentecostais e a

  2019-05-20

  

  De acordo com algumas pesquisas os (neo) pentecostais e a rcc colaboraram de forma decisiva para o ressurgimento na liturgia cristã no país da transformação moral dos indivíduos, do ideário da família e da rígida moral sexual. No caso da Igreja católica, o avanço do projeto moral da rcc promoveu um

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