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br Methods and materials br Cyclooxygenase COX is the key
2019-08-21
Methods and materials Cyclooxygenase (COX) is the key enzyme required for the conversion of arachidonic Colistin Sulfate to prostaglandin, prostacyclins and thromboxanes., , , Two distinct isoforms of COX were initially discovered: COX-1 is a constitutive, housekeeping enzyme that is expresse
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br Author contribution br Acknowledgements QNRF grant number
2019-08-21
Author contribution Acknowledgements QNRF grant number NPRP6-065-3-012, Qatar National Research Fund, Doha Qatar for funding this work with grant number NPRP No.: NPRP6-065-3-012. Introduction Preeclampsia (PE) affects 3–5 % of pregnancies worldwide and is one of the leading causes of mate
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Coumarins also known as benzopyran ones are a
2019-08-21
Coumarins also known as benzopyran-2-ones are a family of nature-occurring lactones first isolated from Tonka beans in 1820. They are an important class of oxygen containing heterocycles widely found in nature, so much so that they have been routinely employed as herbal remedies since early days. Ov
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Table summarizes the literature data available on
2019-08-21
Table 4 summarizes the literature data available on the occurrence of these two pgds inhibitor of steroidal compounds in sludge and sediments. In activated and digested sewage sludge, the concentrations of ethynyl estradiol (17 ng/g), estrone (37 ng/g ), and estradiol (49 ng/g) found in one of the
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br Materials and methods br Results br Discussion This
2019-08-21
Materials and methods Results Discussion This study demonstrates that various progestogens combined with E2 had different effects on breast cell growth. These effects had an inverse correlation with the changes of the PRA/PRB ratio. E2\'s antiapoptotic effects on MCF-7 melanotropin msds ma
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Prostanoids typically act in an autocrine and paracrine fash
2019-08-21
Prostanoids typically act in an autocrine and paracrine fashion by binding to specific receptors in target hdac inhibitors and there is evidence that both PGE2 and prostacyclin may be required for the optimal activation of angiogenesis (Hata and Breyer, 2004). PGE2 and prostacyclin bind to their sp
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In vitro studies suggest that cPLA does
2019-08-21
In vitro studies suggest that cPLA2α does not show clear preference for the headgroup present at the sn-3 position, although a slight preference for zwitterionic phospholipids such as PC and PE has recently been pointed out [24]. In this regard, mass spectrometry analyses of glycerophospholipid hyd
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br Conclusion br Limitations br Conflict of interest
2019-08-20
Conclusion Limitations Conflict of interest Financial disclosure The research was supported by National Institute of Mental Health and Neuro Sciences (NIMHANS)Intramural Research Grant ID NIMH/PROJ-RSM/545/2014-15. India. Acknowledgments Introduction Increased central and peripher
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Moreover the imbalance between pro and
2019-08-20
Moreover, the imbalance between pro and anti-inflammatory cytokine production is present in various types of diseases. The use of substances able to induce anti-inflammatory cytokines could represent an important advance in the therapeutic treatment of a range of diseases. In this context, medicinal
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br Author contributions br Funding M E
2019-08-20
Author contributions Funding M.E.B. was supported by Research Fund #3096. Competing interests Introduction Lung cancer has become one of the most common death causes in both male and female malignant tumors (Jemal et al., 2011). Air pollution, smoking and estrogen level are known risk f
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Many researchers studied the experimental investigation of R
2019-08-20
Many researchers studied the experimental investigation of RHA in cement enhances the strength and durability of the concrete [9], [10], [11], [12]. It is most important that concrete must withstand its strength even after it is being exposed to any corrosive environment over a period of time. In ad
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The preceding results show no association
2019-08-20
The preceding results show no association between the EP1 gene polymorphisms and suicide completers in the Japanese population. Impulsive aggression is one of the most important risk factors for suicide especially in the younger generation (Brent et al., 2002, Melhem et al., 2007). EP1 knockout mice
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It has been reported that PGE
2019-08-20
It has been reported that PGE2 increases expression of the survivin mRNA (Baratelli et al. 2005) and promotes the stabilization of the survivin protein in some tumor Mevastatin (Krysan et al. 2003). However, it is unclear whether PGE2 affects the expression of survivin mRNA or promotes the stabiliz
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The redox sensitive transcription factor NF B
2019-08-20
The redox sensitive transcription factor NF-κB is reported to play a crucial role in the COPD pathogenesis via up regulating the expression of several cytokines, chemokines, growth factors, and adhesion molecules [71]. Incidentally, we and others have shown that PARP-1 modulates the NF-κB activation
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br Materials and methods br Results and
2019-08-20
Materials and methods Results and discussion Conflict of interest Acknowledgments This work was supported by grants from National 973 Project (2015CB755700) and the Doctoral Starting up Foundation of Henan University of Science and Technology (13480033). Introduction Progression thro
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