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br Methods br Results br Discussion Adiponectin
2022-11-05
Methods Results Discussion Adiponectin is naturally expressed and secreted exclusively from adipocytes, and adiponectin levels and its isoforms in circulation have recently been reported to highly associate with human coronary artery disease (CAD) [46], [47], [48], [49], these studies clear
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br Introduction The chronic inflammation is one of the
2022-11-05
Introduction The chronic inflammation is one of the leading events involved in the aetiology of many chronic-degenerative diseases including diabetes, atherosclerosis, arthritis and cancer (Coussens and Werb, 2002). Monocytes/macrophages lineage plays an important role during inflammation through
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The following are the supplementary data related to
2022-11-05
The following are the supplementary data related to this article. Conflict of interest Acknowledgements Disclosure of interest Introduction Since the introduction of platinum-based chemotherapy, metastatic testicular cancer has become a curable disease and most testicular cancer patient
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br Discussion The measurement of gonadotropins
2022-11-05
Discussion The measurement of RN 1734 (FSH, LH) is critical in the evaluation and assessment of 46,XX females presenting with primary amenorrhea and lack of pubertal development. A serum level of FSH higher than 40 U/L is diagnostic of ovarian failure (6), as seen in the present case. The most c
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calcitonin receptor Chronic inflammation is associated with
2022-11-05
Chronic inflammation is associated with both initiation and progression of many neoplastic conditions [149], and ATX may be a player in the process. ATX/LPA signaling is positively correlated with the invasive and metastatic potential of several cancers including melanoma, breast cancer, ovarian can
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Cytarabine br ACL Regulation and Role
2022-11-05
ACL Regulation and Role in Lipid Metabolism ACL is a ubiquitous enzyme at the nexus of nutrient catabolism and synthesis of cholesterol and fatty acids. In mammals, it is highly expressed in lipogenic tissues including adipose, liver, and lactating mammary glands [9]. In the presence of ATP and C
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To evaluate the ability of both sets of compounds
2022-11-05
To evaluate the ability of both sets of compounds to inhibit the activity of 15-LOX an initial screen was performed, whose results are shown in . The comparison of inhibition values would seem to indicate that, in the HYD series, an electron donor group at the position increases and an electron at
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The compounds containing beryllium act as strong Lewis acids
2022-11-05
The compounds containing beryllium act as strong Lewis acids because of electron deficiency of the Be Cy7.5 NHS ester (non-sulfonated) []. Interactions of X-Be-Y compounds with different Lewis bases have been studied by Yanez and co-workers [], extensively. Recently, they proposed a class of extrem
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According to the diversity in molecular skeletons aromatase
2022-11-05
According to the iox receptor in molecular skeletons, aromatase inhibitors can be categorized into two types: steroidal and non-steroidal blockers [6]. Steroidal AI (e.g., exemestane in Fig. 1) derived from the substrate androstenedione interacts with aromatase through chemical actions, resulting i
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gamma-Glu-Cys By contrast with a plenty of our understanding
2022-11-05
By gamma-Glu-Cys with a plenty of our understanding on arginine metabolism in animals and higher plants, very little thus far is known on the specific function of arginase that acts as a key control point for keeping arginine balance in edible mushrooms and neither for its physiological role in pos
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Despite the absence of disulfide bonds in its
2022-11-04
Despite the absence of disulfide bonds in its linear structure, KT43C displays antifungal and antibacterial activity. Disulfide bonds are determinants of defensins' integrity and have been reported to increase the antimicrobial activity (Jenssen et al., 2006). However, some linear derivatives of AMP
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Due to metabolic variations it is important
2022-11-04
Due to metabolic variations, it is important to consider arginine metabolism and dependency in specific contexts to identify precise patterns. This is best illustrated for ASS: while ASS deficiency correlates with worse prognosis in sarcomas, ASS levels positively correlate with a poor prognosis in
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Polycyclic aromatic hydrocarbons PAHs are abundant
2022-11-04
Polycyclic aromatic hydrocarbons (PAHs) are abundant environmental contaminants that are produced by the incomplete combustion of organic matter, combustion engines, residential heating, Galanthamine HBr burning, and industrial activities (Gelboin, 1980; Phillips, 1999, Phillips, 2002). Some PAHs ha
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The biology of the A BR is
2022-11-04
The biology of the A2BR is complex and needs to be considered contextually as the expression and effect of receptor engagement varies according to time post hypoxic injury, cell type and downstream signaling pathway. For example, A2BR expression is dynamic - low under basal and increasing under isch
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flavopiridol br Materials and methods br Results br Discussi
2022-11-04
Materials and methods Results Discussions Diabetes is mainly divided into Type 1 diabetes and Type 2 diabetes [16]. Type 2 diabetes, featured by insulin resistance, results from environmental factors and poor eating habits [2]. Type 2 diabetes accounts for more than 95% of the diabetic pati
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