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In September a high level meeting
2019-04-18
In September 2011, a high-level meeting of the UN called for a concerted global response to the growing challenge of non-communicable diseases (NCDs). Subsequently, in 2013, the World Health Assembly adopted a WHO-generated action plan and set a target of 25 × 25: a 25% reduction in premature mortal
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La nueva escritura del Quijote que emprende
2019-04-18
La nueva escritura del Quijote que emprende Menard resulta a la vez, en gran paradoja, la más fiel y la más infiel, la transcripción total y la adaptación libérrima, y llega incluso a la reducción al absurdo de las leyes del homenaje literario: especie de homenaje por sus antípodas, ya que se omite
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Brasil y Argentina son los dos pa ses que
2019-04-17
Brasil y Argentina son los dos países que comparten fronteras con todos los países restantes del bloque primigenio. Aun así, sus legislaciones abordan el tema en menor profundidad en comparación serotonin receptor como lo hacen Paraguay y Uruguay. En Brasil, la Ley 11445 es la que refleja en cierta
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In order to treat metastatic bone disease effectively all
2019-04-17
In order to treat metastatic bone disease effectively all steps involved in the metastatic cascade need to be taken into account as for example the interactions between primary and secondary sites, tumour cell–bone cell cross talk and osteomimicri [8]. Therefore, concomitant targeting of both the tu
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br Methods br Results br Discussion Analyses of basal syndec
2019-04-17
Methods Results Discussion Analyses of basal syndecan-1 expression showed differences in syndecan-1 levels as well as staining pattern for this proteoglycan in the breast cancer cell lines that were employed. Different localization of syndecan-1 have been found in previous studies showing l
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Introduction Osteosarcoma OS is the most
2019-04-17
Introduction Osteosarcoma (OS) is the most commonly diagnosed histological form of primary bone tumor with high morbidity, and it is mainly prevalent in teenagers and young people [1]. Pain is the most common early symptom of OS and can cause fracture of the affected bone. Currently, multiple thera
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Sultan et al retrospectively searched the surveillance epide
2019-04-16
Sultan et al retrospectively searched the surveillance, epidemiology, and end results (SEER) database for patients who were diagnosed with NPC from 1988 to 2006. They compared the clinical features and outcomes of 129 children and adolescents (n and young adults compared with older adults with nasop
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NAFLD and fatty liver is the accumulation of
2019-04-16
NAFLD and fatty liver is the accumulation of fat and cholesterol in hepatocytes. NAFLD is one of the most common liver diseases in the USA and worldwide. NAFLD is associated with obesity, inflammation and insulin resistance. Fat accumulation in the liver is due to the uptake and synthesis (intake) o
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Of indicators in the Index ten fulfilled all comparability
2019-04-16
Of 101 indicators in the Index, ten fulfilled all comparability criteria for the detailed longitudinal analysis, and six core-scored indicators with the highest correlation with overall scores were used for the detailed longitudinal analysis. We made several important observations. First, the crude
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Uric acid level was high at presentation but
2019-04-16
Uric line level was high at presentation but not at a level where nephropathy is usually expected. Yet, uric acid increased with creatinine until administration of rasburicase. Whether this increase was enough to cause or contribute to the ARF is uncertain. Comparably, Larsen and Loghman-Adham repor
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br Case report A year
2019-04-16
Case report A 73 year-old man was diagnosed with chronic lymphocytic lymphoma (CLL) in December 2009, where he presented with a servical mass at another state hospital. He was treated with 6 cycles of cyclophosphamide, vincristine and prednisone (CVP). On follow-up he received 6 cycles of fludara
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Additionally the expression of AMH in GCs
2019-04-16
Additionally, the expression of AMH in GCs treated with BMP15 + SB203580 was significantly decreased compared with that in GCs treated with BMP15 alone; thus, it was further demonstrated that BMP15 can up-regulate the expression of AMH by activating the p38 MAPK signaling pathway. However, the expre
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Since the first description of epicardial VT ablation
2019-04-16
Since the first description of epicardial VT ablation with percutaneous subxiphoid access in 1996, epicardial mapping and ablation have been widely performed for the treatment of scar-related VT [55]. Svenson et al. reported that orexin receptor epicardial VT circuits are particularly common in pati
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Durrer et al reported that ventricular depolarization begins
2019-04-16
Durrer et al. [17] reported that ventricular depolarization begins in the LV septum, which suggests that initiating pacing from regions close to this area (e.g., RV septum) may produce a physiologic contraction pattern. In contrast, the free wall of the RV is the last zone to be depolarized. Thus, i
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In patients who develop bone metastases these are commonly
2019-04-16
In patients who develop bone metastases, these are commonly diagnosed at the time of their initial work up for their metastatic disease (∼80%) [7], although others can develop skeletal metastases at any time during the disease course. The consequences of bone metastases include pain (∼80%) [3,6,8] a
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