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A su vez Paraguay expresa claramente en
2019-06-12

A su vez, Paraguay expresa claramente en la Ley 3239, Artículo 3, inciso H que se tiende “[…] bmn 673 la economía en el uso de los recursos hídricos. a través de su utilización racional y eficiente, posibilitando, así la disponibilidad para otros usos, previendo sobre su derroche, contaminación y de
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br Introduction Once metastatic breast cancer
2019-06-11

Introduction Once metastatic breast cancer rxr receptor are in the bone marrow, they hijack signals coming from the normal bone remodelling process and promote bone degradation [1]. Bone degradation is caused by osteoclasts, which have the unique property to dissolve bone mineral and degrade the
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Additionally the selection for subcutaneous ICD implant is b
2019-06-11

Additionally, the selection for subcutaneous ICD implant is based on pre-implant electrographic body surface mapping. The sensing algorithm for this system depends on the surface elecrtrocardiogram (ECG) morphology, specifically the R-and T-wave amplitudes, R/T and R/P ratios, QRS duration and QT in
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br Conflict of interest br Introduction
2019-06-11

Conflict of interest Introduction Cholangiocytes Cholangiocytes are epithelial lipoxygenase lining the intra and extrahepatic ducts of the three-dimensional network of the biliary tree. Biliary cells comprise approximately 3–5% of cells in the liver and are considered as one of the main ce
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br We appreciate the response by Sharath
2019-06-11

We appreciate the response by Sharath Nagaraja and Ritesh Menezes to our Comment, in which we had argued that patients with tuberculosis deserve a complete and patient-centric solution, irrespective of whether they seek care in the public or private health sector. Nagaraja and Menezes seem to have
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There are major challenges in
2019-06-11

There are major challenges in the estimation of the prevalence of opioid use in Afghanistan. The country has been in a state of war and insurgency for the better part of 40 years; its order GW788388 is widely dispersed and often very mobile; it has low levels of literacy; and Afghans are not accust
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Las l neas le comunican a Felipe
2019-06-11

Las líneas le comunican s6 kinase Felipe que él y sus marañones habían determinado salir De lo primero, denuncia la perversidad de la administración, encabezada por el virrey Cañete, “malo, lujurioso, ambicioso tirano”, quien “premió” a los hombres que combatieron la rebelión de Hernández Girón con
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We established Wt and two
2019-06-11

We established Wt- and two Mt- (p.R308P and p.A350_N351ins8)-GATA2-expressing 32D 69 9 to analyze the cellular effects of Mt-GATA2 (Fig. 3A). Immunofluorescence analysis revealed that Mt-GATA2 showed similar localization in the nucleus as Wt-GATA2 (Fig. 3B). Both Wt- and mutant-GATA2-expressing 32D
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LYL belongs to the basic
2019-06-11

LYL1 belongs to the basic helix-loop-helix (bHLH) transcription factor family, which plays important roles in a variety of developmental processes, including hematopoiesis [6]. The biological function of LYL1 is largely unknown, but its expression is restricted to hematopoietic cells, including myel
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br CaMKII and heart failure progression CaMKII is a multifun
2019-06-11

CaMKII and heart failure progression CaMKII is a multifunctional serine–threonine kinase, phosphorylating target proteins. Under resting conditions, CaMKII is inactive. A rise in intracellular Ca2+ stimulates binding of Ca2+ to calmodulin (CaM), a ubiquitous Ca2+-binding protein. The Ca2+/CaM com
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Atrial fibrosis is one of the fundamental mechanisms for
2019-06-11

Atrial fibrosis is one of the fundamental mechanisms for the pathogenesis of atrial fibrillation (AF), but the underlying electrophysiological changes involved are not completely understood. Aging, neurohumoral activation, and chronic atrial stretch due to structural heart disease activate various s
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In the s several hospital based surveys
2019-06-11

In the 1990s, several hospital-based surveys were reported. In a survey of AF among 2686 acute medical admissions to a district general hospital in Glasgow, UK [4], the prevalence of AF was 6.3%, with the predominant associated medical conditions being ischemic heart disease, hypertension, and valvu
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br Methods br Results br
2019-06-11

Methods Results Discussion Bisphosphonates reduce skeletal morbidity in patients with advanced cancers involving bone and have become a recommended component of the multidisciplinary treatment of MBD [1]. However, bone-health benefits have not generally translated into significantly improve
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Como se puede advertir en la narraci
2019-06-10

Como se puede advertir en la narración de Cuadra o, más claramente, en la encuesta que elaboró Téfel, hay toda una toma de conciencia en los sectores medios e intelectuales respecto ccr5 antagonist los pobres. Esta nueva conciencia proyectó también la necesidad de integrar la racionalidad nacional a
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chir99021 Methods Between and Ridge Regional Hospital
2019-06-10

Methods Between 2013 and 2015, Ridge Regional Hospital adopted a quality improvement programme in three stages. In the first stage, two senior staff members were selected to serve as QI (quality improvement) leaders and received 4 days of training in Six Sigma methods. In the second stage, two front
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